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Technical Bulletins (Farm Animal)

Antibiotic & Antimicrobial Stewardship: Disinfectants are Ongoing Focus of Sensitivity, Resistance Debate

Antibiotic resistance has become a significant topic of importance as antibiotic resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria. Given the growing problem of antibiotic resistance, environmental cleaning and disinfection can play an important role in helping to prevent the spread of antibiotic resistant bacteria. As such, there is a growing body of evidence to demonstrate the effectiveness of environmental cleaning and disinfection as part of multimodal strategies to reduce pathogen transmission, prevent infections and improve patient outcomes.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

(USP 800) Hazardous Drugs

Accelerated Hydrogen Peroxide® (AHP®) is a Health Canada and EPA registered disinfectant which continues to gain popularity as one of the most effective and safest disinfectant chemistries in the market. AHP® is highlighted in the United States Pharmacopeia (USP) as the product with a perfect balance between efficacy, safety and compatibility, revealing the technologies potential within compound pharmacy. In the latest revision of Hazardous Drugs - Handling in Healthcare Settings, hydrogen peroxide was frequently mentioned as an effective chemistry for the deactivation of hazardous drugs (HDs), which reinforces AHP® as an accepted disinfectant in the Pharmaceutical Industry.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

(USP 797) Pharmaceutical Compounding-Sterile Preparations

Accelerated Hydrogen Peroxide® (AHP®) is continuing to gain popularity as one of the most effective and safest disinfectant chemistries. AHP® is highlighted in the United States Pharmacopeia (USP) as THE product with a perfect balance between efficacy, safety and compatibility, revealing the technologies potential within compound pharmacy. The inclusion of AHP® in the most recent USP edition reinforces AHP® as an accepted disinfectant in the Pharmaceutical Industry.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Selection of the Ideal Disinfectant

This article reviews the 5 key criteria that should be used when evaluating disinfectant products today.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Antibiotic and Antimicrobial Stewardship: Disinfectants are Ongoing Focus of Sensitivity, Resistance Debate

Much less is known still about microorganisms’ reduced sensitivity to germicides such as surface disinfectants. There have been some studies indicating that imprudent use of chemicals can encourage the beginning stages of resistance, but experts have not reached consensus on this issue. However, daily environmental surface disinfection can reduce the amount of antibiotic resistant pathogens in the healthcare environment and help prevent their spread.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Efficacy of Green Cleaning Products with Respect to Common Respiratory Viruses and Mold Growth

While mechanical cleaning with a GCP may physically remove harmful pathogens from a surface, effective control against the spread of infection truly requires the use of EPA or DIN registered disinfectants

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

pH

The pH is relevant, because it shows us if the solution is acidic, neutral or alkaline but a pH value alone is not the sole indicator in determining the strength of different types of acids

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Enhanced inactivation of avian influenza virus at -20°C by disinfectants supplemented with calcium chloride or other antifreeze agents

Dr. Guan et al. Antifreeze agents can be added to Accel® to ensure the disinfectant remains in liquid form at -20°C, without compromising the efficacy of AHP® against AIV.

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Topics: Technical Bulletins (Farm Animal)

Effects of disinfection on the molecular detection of PEDv

The purpose of this study was to examine the effect of disinfectants on RT-PCR results for PEDv and explore the practical solutions to produce RT-PCR engative trailers after they have been contaminated with PEDv. AHP was included in the study and was one of the only chemestries to produce negative RT-PCR results

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Topics: Technical Bulletins (Farm Animal)

Comparison of disinfectant efficacy when using high-volume directed mist application of AHP and peroxymonosulfate disinfectants in large animal hospitals

The purpose of this study was to compare the efficacy of 2 disinfectant solutions: 4.25% AHP at 1:16 dilution and peroxymonosulfate solution as a high-volume directed mist application

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Topics: Technical Bulletins (Farm Animal)

Efficacy of endotracheal tube disinfection strategies for elimination of Streptococcus zooepidemicus and Bordetella bronchiseptica

Drs. Crawford and Weese looked at various strategies for reprocessing ETs, including using AHP.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Efficacy of eight commercial disinfectants against Microsporum canis and Trichophyton spp: infective spores on an experimentally contaminated textile surface

Dermatophytosis (ringworm), a highly contagious skin infection, is caused by fungus leading to a circular rash on animals and humans. Due to the highly contagious nature of dermatophytosis, proper disinfection of affected surfaces is essential. This study considers a relatively new yet proven chemistry, broadly used in healthcare facilities, known as Accelerated Hydrogen Peroxide® (AHP®), in contrast with current chemistries that have known shortcomings.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Canadian Government to Ban or Restrict Toxic Chemicals

On Friday December 8th 2006, Prime Minister Stephen Harper announced a “substantial investment in public funds” to clean up dangerous chemicals in the environment. The list of chemicals includes some already proven harmful to animals and suspected to be potentially harmful to human health. Every two or three months, a list of suspect chemicals will be released in groups of 15 to 30. Industry and stakeholders will be required, within six months, to provide information the government about the chemicals. If the government is not satisfied by the response, industry will be required to take action which in some cases may mean industry would be required to provide alternative materials. In conjunction with the announcement, the government also launched a Chemical Substance website which details how the assessments will work and provides links to fact sheets on chemical impact to human health, and government resources and processes for managing chemical assessments. The website also includes a list of chemicals not banned but regulated and of “interest to Canadians” because of the risks associated with them. Two of these chemicals, 2-Butoxyethanol and 2-Methoxyethanol, are of significant interest to the cleaning and disinfection industry as they are commonly used as solvents in both cleaners and disinfectants.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Calculating Product Concentrations

To ensure optimal cleaning or disinfection it is important that products are used at the dilution ratio specified on the product label. From time to time Public Health or Infection Control may request that the dilution control systems be tested to confirm the products are being diluted appropriately so it is important to know how to calculate Use Dilution concentration. This document reviews the simple formulation to help you achieve proper dilution to ensure Accelerated Hydrogen Peroxide's ® (AHP®) maximum efficacy.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Is ph an appropriate indicator of product safety?

There is much confusion among cleaning and disinfectant users regarding pH and what it means with respect to a product's cleaning or killing properties, its materials compatibility as well as its rating with regards to its toxicity / hazard profile. The intent is to dispel these misunderstandings and provide the facts to help increase your confidence in your choice of cleaning or disinfectant chemistry.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Biofilms

Biofilms are nothing new to our world. They can be found in any environment that has a flow of water and a contact surface. Biofilms can be deleterious or beneficial depending on where they are found and which organisms they are comprised of. As a society, however, we most commonly associate the issue of biofilms with their related infections. Examples of these are otitis media and bacterial endocarditis, which are caused by bacteria entering a fluid filled part of the body. Accelerated Hydrogen Peroxide® (AHP®) is relatively new yet proven technology that has gained a reputation as being one of the most effective yet safe technologies on the market. In fact, two studies have been conducted using AHP highlighting its ability to kill and remove biofilms. This document will help you and decision makers to better understand what Biofilms are and the relevance of using a disinfectant capable of killing and removing them.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Efficacy of Green Cleaning Products with Respect to Common Respiratory Viruses and Mold Growth

As infection prevention concerns continue to move mainstream into our communities, so too does the increased usage of cleaning chemicals and disinfectants. The increased usage of many of these chemistries has the potential to negatively impact the environment and therefore, many end users are searching for “greener” alternatives. A major concern in this trend is the implementation of cleaning products that are simply ineffective in killing certain microorganisms. The increasing prevalence of hydrogen peroxide, an environmentally preferable ingredient with limited antimicrobial efficacy on its own, has the potential to exacerbate this concern. Many manufacturers of hydrogen peroxide based cleaners are positioning their products as effective disinfectants without validation leading to potential misperception. This article also highlights the results of an evaluation of Green Cleaning Products (GCPs) and Traditional Surface Disinfectants (TSDs) and their respective efficacy against common respiratory viruses and mold.

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Topics: Technical Bulletins(Companion), Technical Bulletins (Farm Animal)

Battling germs that keep getting stronger

Battling Germs That Keep Getting Stronger, an article appearing on www.cbc.ca, highlights the emergence of antibiotic resistant organisms (AROs) in the community and the potential role certain antibacterial products play in the development of such resistance. AHP surface disinfectant cleaners exhibit broad spectrum germicidal efficacy in rapid and realistic contact times. Hydrogen Peroxide, the active ingredient in Accelerated Hydrogen Peroxide® (AHP®), does not remain on the surface once it has dried, hence it does not provide the opportunity for bacteria to develop resistance to it. Therefore, AHP surface disinfectant cleaners can be used safely and effectively to reduce bacterial contamination on surfaces.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Quality Control is Indispensible for Automated Dilution Systems with Accelerated Hydrogen Peroxide

Accelerated Hydrogen Peroxide® (AHP®) is a patented synergistic blend of commonly used, safe ingredients that when combined with low levels of hydrogen peroxide dramatically increase its germicidal potency and cleaning performance. To ensure maximum efficacy, AHP concentrated products can be diluted with automated dilution control systems. However, just as we wouldn't run our automobiles without regular oil changes and tire rotations, so to we shouldn't operate these systems without regularly scheduled preventative maintenance. This evaluation focused on an AHP disinfectant and its associated dilution system to emphasize the importance of performing quality checks on other hospital grade disinfectants that are diluted and dispensed from automated control systems.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Pork producers have another option for disinfecting against PEDv

With the advent of devastating diseases affecting the swine industry, much attention is being given to biosecurity in an effort to improve hygiene and ultimately prevent the spread of pathogens. As such, industry is looking to new chemical formulations, vetted protocols and scientific support data as a front line defense to ideally prevent disease, and when required eradicate an outbreak. This study considers a relatively new yet proven chemistry broadly used in healthcare facilities known as Accelerated Hydrogen Peroxide® (AHP®) in contrast with current chemistries that have known shortcomings. The third party study conducted by the renowned University of Iowa shows that AHP is superior to the incumbent chemistries tested.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

An evaluation of the effectiveness of sanitation procedures using an accelerated hydrogen peroxide (Accel) disinfectant to reduce virus transmission via livestock transport vehicles

Disease outbreaks within the swine industry can be devastating with mass economical costs. With the constant threat of disease emergence, industry is looking to new chemical formulations, vetted protocols, and scientific support as a front line of defense for their biosecurity. This study tests the efficacy of a relatively new yet proven chemistry that is broadly used in healthcare facilities known as Accelerated Hydrogen Peroxide® (AHP®), recognized for its superior cleaning ability and realistic contact times, ensuring disinfection has taken place.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Disinfection the critical step in aquaculture and intensive farming

From the production farm to the processing plant, hygiene is of major importance to prevent the dispersion of microorganisms, minimize the risk of related diseases and ensure safe food. Dramatic epidemic outbreaks remind everybody of the necessity to implement hygiene and biosecurity measures along the food production chain. A critical step in biosecurity programs is choosing a reliable disinfectant to ensure healthy animals and safe food. This document outlines the critical steps in disinfection to ensure your facility is protected against these dangerous pathogens. Accelerated Hydrogen Peroxide® (AHP®) is a revolutionary disinfectant technology that has superior benefits to legacy disinfectants with known shortcomings and should be considered as an essential aspect of biosecurity programs.

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Topics: Technical Bulletins (Farm Animal)

Evaluating Post-Milking Teat Dip Efficacy Using Somatic Cell Count Data

Teat dipping is an essential practice in preventing new intramammary infections in cows. The procedure involves dipping teats of dairy cows before and after milking with a germicidal solution to reduce teat skin colonization and contamination with mastitis-causing bacteria and minimize penetration. Chlorhexidine is a commonly used teat disinfectant, as it is recognized for its rapid action and residual activity against intramammary infections. However, it is also known for causing anaphylactic reactions and bioaccumulation in the environment causing reactions to form more toxic-bi-products. With these concerns in mind, Accelerated Hydrogen Peroxide® (AHP)® products have been found to be non-hazardous, non-irritating to skin or respiratory tract. Furthermore, hydrogen peroxide breaks down into water and oxygen reducing environmental impact.

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Topics: Technical Bulletins (Farm Animal)

Guideline to Controlling Infectious Folliculitis and Dermatophytosis in Equine

Bacterial, dermatophilosis and superficial ringworm infections are common skin diseases noted in equine dermatology. The ability to recognize and accurately diagnose the skin condition is key to selecting an appropriate and successful treatment regimen. Accelerated Hydrogen Peroxide® (AHP®) is a leading disinfectant technology in the human health market and is becoming increasingly recognized as the cleaner, faster and safer disinfectant technology within the animal health market. Known for its germicidal potency, yet incredible safety profile, this guideline validates the use of AHP within the Equine market.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Infection Prevention and Control Best Practices for Small Animal Veterinary Clinics

This document was developed by the Canadian Committee on Antibiotic Resistance and is intended to guide clinical practice and provide assistance for decision-making on infection prevention and control issues. Furthermore, this document is designed to provide a complete and readily accessible summary of infection prevention and control best practices for small animal veterinary clinics, and is intended to be understandable to all members of the veterinary practice team.

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Topics: Technical Bulletins (Farm Animal)

Efficacy of Two Hydrogen Peroxide Teat Disinfectants Against Staphylococcus aureus and Streptococcus agalactiae

The process of pre-milking udder preparation and post-milking teat disinfection are widely accepted as integral components of a successful mastitis control program. The dairy industry continues to seek efficacious alternatives to iodophore-based post-milking teat disinfectants that have the ability to achieve high efficacy of bactericidal activity while maintaining the integrity of the teat skin condition. This study aims to assess the efficacy of a new Accelerated Hydrogen Peroxide ® (AHP®) teat disinfectant against a commonly used industry competitor.

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Topics: Technical Bulletins (Farm Animal)

Effects of disinfection on the molecular detection of porcine epidemic diarrhea virus

Routine detection of porcine epidemic diarrhea (PEDv) is currently limited to RT-PCR testing, as it is the only test method that can directly detect PEDv. Because RT-PCR only detects the viral RNA, a positive RT-PCR result only indicates the presence of PEDv viral RNA, but does not mean viable and infectious virus is present. Accelerated Hydrogen Peroxide®(AHP®) is a relatively new yet proven technology that is capable of disinfecting PEDv but may still leave inactivated RNA strands on surfaces, and therefore has a history of producing RT-PCR positive test results. In this study AHP was tested along with a number of other disinfectant actives as agents against PEDv using RT-PCR. Positive RT-PCR results were tested to show how AHP was able to fully inactivate any remaining RNA on the surface. Therefore AHP can be used as an alternative disinfectant that is effective against PEDv without the negative toxicity, environmental, safety and compatibility profiles.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)

Assessment of Accelerated Hydrogen Peroxide® disinfectant wipes in removal of chemotherapeutic agents from hard non-porous environmental surfaces.

Chemotherapy molecules are known to be highly resistant to inactivation by chemical disinfectants. In order to protect personnel preparing chemotherapy drugs, choosing a disinfectant with the ability to cleanse or degrade chemotherapy agents is an essential.

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Topics: Technical Bulletins (Farm Animal), Technical Bulletins (Companion Animal)