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Should the AOAC Use-Dilution Method Be Continued for Regulatory Purposes?

The study reviews UDM from a statistical perspective, identifying significant gaps in the reproducibility of the test data as predicted by statistical analysis and those presented to the EPA for product registration. UDM’s poor reproducibility, along with its qualitative nature, requires the concentration of the active ingredient to be high enough to ensure all or most carriers to be free of any viable organisms. This is not in accord with the current trends towards sustainability, human safety, and environmental protection.

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Topics: AHP® Peer Reviewed Articles (Companion Animal), AHP® Peer Reviewed Articles (Farm Animal)