Do You Sweat the Small Stuff? Dispelling the Myth of Efficacy Claims

Written by Nicole Kenny | May 10, 2013 6:37:00 PM
Often we allow ourselves to get all worked up about
things that, upon closer examination, aren't really that big a deal. We focus
on little problems and blow them out of proportion.  In the world of infection prevention and
control we see this time and time again. 
Infection prevention and control is not black and white
nor is it one size fits all.  It would
certainly make our lives easier if it were, but the truth of the matter is that
the environmental hygiene processes used to prevent infections will differ from
region to region and facility to facility depending on the patient population
and underlying disease or pathogen prevalence. 
As such the selection and use of liquid chemical disinfectants is
largely a matter of judgement based on the facilities needs.
Example #1 Sweating over a TB claim
One common misconception with respect to label claims is
the purpose of a tuberculocidal claim. 
Historically, tuberculocidal claims have been used as the benchmark of a
product's ability to inactivate a broad-spectrum of pathogens including the far
less resistant bloodborne pathogens (e.g. Hepatitis B or C and HIV).   It is this broad-spectrum capability that
was the original basis for OSHA's regulations for bloodborne pathogens. However
OSHA revised its stance in 1991 to specify that disinfectant products that
carry efficacy claims against HIV and Hepatitis B (HBV) are indeed appropriate
for managing blood and body fluid spills.
Fact:
EPA registered disinfectants with efficacy claims against
HIV and HBV or appropriate for use in cleaning and disinfecting surface that
are contaminated with blood and body fluid. 
Bloodborne pathogens we are concerned with are enveloped EASY TO KILL
viruses.  EPA registered disinfectant
labels include explicit directions for how they can be used against bloodborne
pathogens on their EPA approved label. 
JUST FOLLOW THEM!
Example #2 Sweating over Multiple Contact Times
Varying times listed on a disinfectant's label for
efficacy against various bacteria, viruses, fungi, and mycobacteria causes
angst within the Infection Prevention and Control community because it is
believed by some that the longest kill time on the product as the required
wet/contact kill time. The truth is that surfaces contaminated with organisms
such as Candida, non-tuberculosis mycobacteria and other fungi have rarely, if
ever, been shown to be a risk factor for healthcare-associated infections.  Products with Fungicidal claims can be relevant
when supporting a claim for broad-spectrum disinfection and can be of interest
in situations such as mold or fungal remediation, however, their relevance to
infection prevention and environmental transmission of disease is minimal. 
Fact:
The CDC Guideline for Disinfection and Sterilization in
Healthcare Facilities refers to the time necessary to kill bacteria on surfaces
(i.e., 1 minute) not the kill time for more difficult to inactivate pathogens
such as Mycobacterium tuberculosis which doesn’t even have an environmental
surface mode of transmission. When it comes to disease prevalence, experts all
agree that the primarily causative organisms are either bacteria or viruses and
that the pathogens of concern moving forward will continue to be bacteria or
viruses.  Vegetative bacteria such as S.
aureus, Enterococcus, Eschericihia coli, coagulase-negative Staphylococcus,
Pseudomonas aeruginosa, Klebsiella spp, Enterobacter spp, etc and viruses such
as Influenza and the more difficult to kill Norovirus are the pathogens that
cause the vast majority of healthcare-associated infections.  In fact studies have shown these organisms to
cause upwards of 85-90% of HAIs. (Rutala 
2012)
When choosing a disinfectant product, ask yourself: what
is relevant to my facility and my patients? 
If your surveillance and outbreak data reflects the fact that 90% of
your concerns are due to vegetative bacteria and viruses, focus your attention
on a disinfectant formulation that provides you with a responsible balance
between effectiveness - broad spectrum coverage against gram negative and gram
positive vegetative bacteria and both enveloped and non-enveloped viruses; and
minimal toxicity – results in greater user compliance.  


Bugging Off!

Nicole