Virox Animal Health

Revolutionary Disinfectants for Infection Control & Biosecurity

Technical Bulletins

In vitro efficacy of shampoos against Microsporum canis and Trichophyton species.

Due to the highly contagious nature of dermatophytosis, proper disinfection of affected surfaces is essential, and treatment of the animal/human is a top priority. Treatment involves systemic antifungal drugs, which eliminate the infection within the hair follicle, and repeated use of a topical antifungal therapy for disinfection of the hair coat.

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Assessment of Accelerated Hydrogen Peroxide® disinfectant wipes in removal of chemotherapeutic agents from hard non-porous environmental surfaces.

Chemotherapy molecules are known to be highly resistant to inactivation by chemical disinfectants. In order to protect personnel preparing chemotherapy drugs, choosing a disinfectant with the ability to cleanse or degrade chemotherapy agents is an essential.

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The National White-Nose Syndrome Decontamination Protocol

White-Nose Syndrome (WNS) in hibernating bats is a fungus that grows on a bats nose, wings and ears and is highly transmissible between bats and also by human-assisted transmission from cave to cave. Caving is becoming more popular, either from a scientific point of view or recreationally. The fungus is causing severe mortality within bat populations across the United States and eastern Canada.

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Evaluation of the Efficacy of Disinfectant Footmats for the Reduction of Bacterial Contamination on Footwear in a Large Animal Veterinary Hospital

Disinfectant footmats and footbaths may be helpful, but are not absolute methods, for eliminating contamination on footwear in veterinary hospital environments. While disinfectant footmats may be considered reliable in decreasing footwear contamination, the magnitude of these decreases is limited. Disinfectant efficacy would likely be improved by the removal of organic debris before disinfection or increasing contact time, however, the study was designed to emulate common practice in livestock hospitals where footmats are utilized to decrease trafficking of microorganisms on footwear as personnel move throughout the facility.

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Efficacy of Accelerated Hydrogen Peroxide®Disinfectant on Foot-and-Mouth Disease Virus, Swine Vesicular Disease Virus and Senecavirus A 

The purpose of this study was to evaluate an accelerated hydrogen peroxide® (AHP®) - based disinfectant against high consequence foreign animal disease pathogens such as foot-and mouth disease virus (FMDV) and swine vesicular disease virus (SVDV), as well as Senecavirus A (SVA), which causes similar lesions as FMDV and SVDV.

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Enhanced inactivation of avian influenza virus at -20°C by disinfectants supplemented with calcium chloride or other antifreeze agents

Avian influenza viruses (AIVs) continue to be a threat to the poultry industry.  Since 2004, there have been at least 6 outbreaks of AIV infection in Canada, and several of these occurred in regions where winter temperatures as low as -20°C are common.  Canada’s eradication policy to control these outbreaks requires euthanizing all birds on infected premises, safely disposing of carcasses and wastes, and then cleaning and decontamination of buildings, vehicles and equipment.

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Kennel Disinfectants for Microsporum canis and Trichophyton sp.

Environmental disinfection is an important component of the prevention and control of dermatophytosis and is of particular importance in facilities housing large numbers of animals such as shelters and boarding kennels. Many factors need to be considered when selecting a kennel disinfectant including, but not limited to, efficacy, lack of toxicity or irritancy to animals and workers, cost, ease of application, and lack of corrosiveness to surfaces. Therefore, a comprehensive analysis was undertaken to determine if Accelerated Hydrogen Peroxide® (AHP®) would be a suitable alternative to other chemistries with known limitations.

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Effects of disinfection on the molecular detection of porcine epidemic diarrhea virus

Routine detection of porcine epidemic diarrhea (PEDv) is currently limited to RT-PCR testing, as it is the only test method that can directly detect PEDv. Because RT-PCR only detects the viral RNA, a positive RT-PCR result only indicates the presence of PEDv viral RNA, but does not mean viable and infectious virus is present. Accelerated Hydrogen Peroxide®(AHP®) is a relatively new yet proven technology that is capable of disinfecting PEDv but may still leave inactivated RNA strands on surfaces, and therefore has a history of producing RT-PCR positive test results. In this study AHP was tested along with a number of other disinfectant actives as agents against PEDv using RT-PCR. Positive RT-PCR results were tested to show how AHP was able to fully inactivate any remaining RNA on the surface. Therefore AHP can be used as an alternative disinfectant that is effective against PEDv without the negative toxicity, environmental, safety and compatibility profiles.

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Comparison of disinfectant efficacy when using high-volume directed mist application of accelerated hydrogen peroxide and peroxymonosulfate disinfectants in a large animal hospital

Effective decontamination of animal holding environments is critical for providing high quality patient care and maintaining a safe working environment. Disinfection of animal holding environments is a significant challenge during times of epidemic disease. This study considers a relatively new yet proven technology Accelerated Hydrogen Peroxide® (AHP®) in the battle against microbes, as an alternative to legacy disinfectant chemistries with known shortcomings.

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Efficacy of Two Hydrogen Peroxide Teat Disinfectants Against Staphylococcus aureus and Streptococcus agalactiae

The process of pre-milking udder preparation and post-milking teat disinfection are widely accepted as integral components of a successful mastitis control program. The dairy industry continues to seek efficacious alternatives to iodophore-based post-milking teat disinfectants that have the ability to achieve high efficacy of bactericidal activity while maintaining the integrity of the teat skin condition. This study aims to assess the efficacy of a new Accelerated Hydrogen Peroxide ® (AHP®) teat disinfectant against a commonly used industry competitor.

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Canadian Standards of Care in Animal Shelters: Supporting ASV Guidelines

Shelter facilities provide a unique challenge for cleaning and disinfection. Animals interact with surfaces within the environment in a far different way than humans and can be adversely impacted by harmful residues left behind on surfaces. Furthermore, many facilities employ volunteers who have little to no background in the safe use of chemicals. Accelerated Hydrogen Peroxide® (AHP®) offers the perfect balance between safety and efficacy, making it the ideal disinfectant chemistry for use in cleaning and disinfection of shelter facilities.

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Infection Prevention and Control Best Practices for Small Animal Veterinary Clinics

This document was developed by the Canadian Committee on Antibiotic Resistance and is intended to guide clinical practice and provide assistance for decision-making on infection prevention and control issues. Furthermore, this document is designed to provide a complete and readily accessible summary of infection prevention and control best practices for small animal veterinary clinics, and is intended to be understandable to all members of the veterinary practice team.

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Guideline to Controlling Infectious Folliculitis and Dermatophytosis in Equine

Bacterial, dermatophilosis and superficial ringworm infections are common skin diseases noted in equine dermatology. The ability to recognize and accurately diagnose the skin condition is key to selecting an appropriate and successful treatment regimen. Accelerated Hydrogen Peroxide® (AHP®) is a leading disinfectant technology in the human health market and is becoming increasingly recognized as the cleaner, faster and safer disinfectant technology within the animal health market. Known for its germicidal potency, yet incredible safety profile, this guideline validates the use of AHP within the Equine market.

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Evaluating Post-Milking Teat Dip Efficacy Using Somatic Cell Count Data

Teat dipping is an essential practice in preventing new intramammary infections in cows. The procedure involves dipping teats of dairy cows before and after milking with a germicidal solution to reduce teat skin colonization and contamination with mastitis-causing bacteria and minimize penetration. Chlorhexidine is a commonly used teat disinfectant, as it is recognized for its rapid action and residual activity against intramammary infections. However, it is also known for causing anaphylactic reactions and bioaccumulation in the environment causing reactions to form more toxic-bi-products. With these concerns in mind, Accelerated Hydrogen Peroxide® (AHP)® products have been found to be non-hazardous, non-irritating to skin or respiratory tract. Furthermore, hydrogen peroxide breaks down into water and oxygen reducing environmental impact.

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Disinfection the critical step in aquaculture and intensive farming

From the production farm to the processing plant, hygiene is of major importance to prevent the dispersion of microorganisms, minimize the risk of related diseases and ensure safe food. Dramatic epidemic outbreaks remind everybody of the necessity to implement hygiene and biosecurity measures along the food production chain. A critical step in biosecurity programs is choosing a reliable disinfectant to ensure healthy animals and safe food. This document outlines the critical steps in disinfection to ensure your facility is protected against these dangerous pathogens. Accelerated Hydrogen Peroxide® (AHP®) is a revolutionary disinfectant technology that has superior benefits to legacy disinfectants with known shortcomings and should be considered as an essential aspect of biosecurity programs.

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An evaluation of the effectiveness of sanitation procedures using an accelerated hydrogen peroxide (Accel) disinfectant to reduce virus transmission via livestock transport vehicles

Disease outbreaks within the swine industry can be devastating with mass economical costs. With the constant threat of disease emergence, industry is looking to new chemical formulations, vetted protocols, and scientific support as a front line of defense for their biosecurity. This study tests the efficacy of a relatively new yet proven chemistry that is broadly used in healthcare facilities known as Accelerated Hydrogen Peroxide® (AHP®), recognized for its superior cleaning ability and realistic contact times, ensuring disinfection has taken place.

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Pork producers have another option for disinfecting against PEDv

With the advent of devastating diseases affecting the swine industry, much attention is being given to biosecurity in an effort to improve hygiene and ultimately prevent the spread of pathogens. As such, industry is looking to new chemical formulations, vetted protocols and scientific support data as a front line defense to ideally prevent disease, and when required eradicate an outbreak. This study considers a relatively new yet proven chemistry broadly used in healthcare facilities known as Accelerated Hydrogen Peroxide® (AHP®) in contrast with current chemistries that have known shortcomings. The third party study conducted by the renowned University of Iowa shows that AHP is superior to the incumbent chemistries tested.

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Quality Control is Indispensible for Automated Dilution Systems with Accelerated Hydrogen Peroxide

Accelerated Hydrogen Peroxide® (AHP®) is a patented synergistic blend of commonly used, safe ingredients that when combined with low levels of hydrogen peroxide dramatically increase its germicidal potency and cleaning performance. To ensure maximum efficacy, AHP concentrated products can be diluted with automated dilution control systems. However, just as we wouldn't run our automobiles without regular oil changes and tire rotations, so to we shouldn't operate these systems without regularly scheduled preventative maintenance. This evaluation focused on an AHP disinfectant and its associated dilution system to emphasize the importance of performing quality checks on other hospital grade disinfectants that are diluted and dispensed from automated control systems.

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Battling germs that keep getting stronger

Battling Germs That Keep Getting Stronger, an article appearing on www.cbc.ca, highlights the emergence of antibiotic resistant organisms (AROs) in the community and the potential role certain antibacterial products play in the development of such resistance. AHP surface disinfectant cleaners exhibit broad spectrum germicidal efficacy in rapid and realistic contact times. Hydrogen Peroxide, the active ingredient in Accelerated Hydrogen Peroxide® (AHP®), does not remain on the surface once it has dried, hence it does not provide the opportunity for bacteria to develop resistance to it. Therefore, AHP surface disinfectant cleaners can be used safely and effectively to reduce bacterial contamination on surfaces.

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Efficacy of Green Cleaning Products with Respect to Common Respiratory Viruses and Mold Growth

As infection prevention concerns continue to move mainstream into our communities, so too does the increased usage of cleaning chemicals and disinfectants. The increased usage of many of these chemistries has the potential to negatively impact the environment and therefore, many end users are searching for “greener” alternatives. A major concern in this trend is the implementation of cleaning products that are simply ineffective in killing certain microorganisms. The increasing prevalence of hydrogen peroxide, an environmentally preferable ingredient with limited antimicrobial efficacy on its own, has the potential to exacerbate this concern. Many manufacturers of hydrogen peroxide based cleaners are positioning their products as effective disinfectants without validation leading to potential misperception. This article also highlights the results of an evaluation of Green Cleaning Products (GCPs) and Traditional Surface Disinfectants (TSDs) and their respective efficacy against common respiratory viruses and mold.

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Biofilms

Biofilms are nothing new to our world. They can be found in any environment that has a flow of water and a contact surface. Biofilms can be deleterious or beneficial depending on where they are found and which organisms they are comprised of. As a society, however, we most commonly associate the issue of biofilms with their related infections. Examples of these are otitis media and bacterial endocarditis, which are caused by bacteria entering a fluid filled part of the body. Accelerated Hydrogen Peroxide® (AHP®) is relatively new yet proven technology that has gained a reputation as being one of the most effective yet safe technologies on the market. In fact, two studies have been conducted using AHP highlighting its ability to kill and remove biofilms. This document will help you and decision makers to better understand what Biofilms are and the relevance of using a disinfectant capable of killing and removing them.

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Is ph an appropriate indicator of product safety?

There is much confusion among cleaning and disinfectant users regarding pH and what it means with respect to a product's cleaning or killing properties, its materials compatibility as well as its rating with regards to its toxicity / hazard profile. The intent is to dispel these misunderstandings and provide the facts to help increase your confidence in your choice of cleaning or disinfectant chemistry.

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Calculating Product Concentrations

To ensure optimal cleaning or disinfection it is important that products are used at the dilution ratio specified on the product label. From time to time Public Health or Infection Control may request that the dilution control systems be tested to confirm the products are being diluted appropriately so it is important to know how to calculate Use Dilution concentration. This document reviews the simple formulation to help you achieve proper dilution to ensure Accelerated Hydrogen Peroxide's ® (AHP®) maximum efficacy.

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Canadian Government to Ban or Restrict Toxic Chemicals

On Friday December 8th 2006, Prime Minister Stephen Harper announced a “substantial investment in public funds” to clean up dangerous chemicals in the environment. The list of chemicals includes some already proven harmful to animals and suspected to be potentially harmful to human health. Every two or three months, a list of suspect chemicals will be released in groups of 15 to 30. Industry and stakeholders will be required, within six months, to provide information the government about the chemicals. If the government is not satisfied by the response, industry will be required to take action which in some cases may mean industry would be required to provide alternative materials.

In conjunction with the announcement, the government also launched a Chemical Substance website which details how the assessments will work and provides links to fact sheets on chemical impact to human health, and government resources and processes for managing chemical assessments. The website also includes a list of chemicals not banned but regulated and of “interest to Canadians” because of the risks associated with them. Two of these chemicals, 2-Butoxyethanol and 2-Methoxyethanol, are of significant interest to the cleaning and disinfection industry as they are commonly used as solvents in both cleaners and disinfectants.

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Efficacy of eight commercial disinfectants against Microsporum canis and Trichophyton spp: infective spores on an experimentally contaminated textile surface

Dermatophytosis (ringworm), a highly contagious skin infection, is caused by fungus leading to a circular rash on animals and humans. Due to the highly contagious nature of dermatophytosis, proper disinfection of affected surfaces is essential. This study considers a relatively new yet proven chemistry, broadly used in healthcare facilities, known as Accelerated Hydrogen Peroxide® (AHP®), in contrast with current chemistries that have known shortcomings.

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Efficacy of disinfectants containing accelerated hydrogen peroxide against conidial arthrospores and isolated infective spores of Microsporum canis and Trichophyton sp.

Dermatophytosis (ringworm), in pets is a skin condition typically cased by fungal infections, more specifically Microsporum canis and Trichophyton sp. Disinfectants, especially sodium hypochlorite (bleach), are commonly used to kill spores not removed during the "hard" cleaning process. Bleach is commonly recommended in the fight against ringworm for its known ability to kill spores. However, it is widely recognized that bleach degrades if not used by the expiry date impacting its efficacy, requires the use of personal protective equipment (as it is a respiratory irritant and can cause damage to the skin and eyes) and has corrosive properties that are known to cause damage to fabrics and surfaces. As a result, a comprehensive analysis was undertaken to determine if Accelerated Hydrogen Peroxide® (AHP®) would be a suitable alternative to sodium hypochlorite.

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